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Updated: Jun 24, 2026

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PI3K活性化腫瘍は,食事制限に抵抗性がある

Nada Y Kalaany1, David M Sabatini

  • 1Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|March 13, 2009
PubMed
まとめ

食事制限は腫瘍の成長に影響しますが,抵抗はフォスファティディル・イノシトール-3-キナーゼ (PI3K) 経路と関連しています. PI3Kの活性化変異により,腫瘍は食事制限に耐性を持ち,標的型療法が示唆される.

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