Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Regulation of Sodium and Potassium01:26

Regulation of Sodium and Potassium

The regulation of sodium and potassium ion concentrations in the human body is a complex process governed primarily by hormones such as aldosterone, antidiuretic hormone (ADH), and atrial natriuretic peptide (ANP).
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily in...
Non-gated Ion Channels01:24

Non-gated Ion Channels

Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism.
Non-gated Ion Channels01:24

Non-gated Ion Channels

Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism.
Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers01:22

Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers

Class I antiarrhythmic drugs are used to treat various types of arrhythmias or irregular heart rhythms. These drugs block the sodium (Na+) channels in the cardiac cells, thereby affecting the movement of electrical impulses across the heart. Class I antiarrhythmic drugs are divided into three subgroups: Class IA, Class IB, and Class IC, each with distinct mechanisms of action and effects on the heart.
Class 1A Antiarrhythmic Drugs: These drugs work by moderately blocking sodium channels,...
Qualitative Analysis03:46

Qualitative Analysis

For solutions containing mixtures of different cations, the identity of each cation can be determined by qualitative analysis. This technique involves a series of selective precipitations with different chemical reagents, each reaction producing a characteristic precipitate for a specific group of cations. Metal ions within a group are further separated by varying the pH, heating the mixture to redissolve a precipitate, or adding other reagents to form complex ions.
For instance, group IV...
Ionic Strength: Overview01:12

Ionic Strength: Overview

The ionic strength of a solution is a quantitative way of expressing the total electrolyte concentration of a solution. This concept was first introduced in 1921 by two American physical chemists, Gilbert N. Lewis and Merle Randall, while describing the activity coefficient of strong electrolytes. During the calculation of ionic strength (I or μ), all the cations and anions are considered. However, the concentration (c) of an ion with a greater charge number (z) has a greater contribution to...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Surprises from a boron-rich semiconductor under pressure.

National science review·2026
Same author

Simple electronegativity-based model for predicting formation of stable compounds across the periodic table.

Nature communications·2025
Same author

Experimental Exchange Interaction Dataset for Magnetic Materials: Spin Waves to MC Simulations.

Scientific data·2025
Same author

Fast Crystallization Driven by Quasiatomic Electrons at Ultralow Temperatures.

Physical review letters·2025
Same author

Structure and adsorption properties of Cu-Au nanoparticles in harsh reactive environments.

The Journal of chemical physics·2025
Same author

Does covalency decrease with coordination number?

The Journal of chemical physics·2025
Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026
Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026
Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026
Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026
Same journal

Dementia risk in middle-aged people linked to a blood protein.

Nature·2026
Same journal

Daily briefing: What's really happening with trust in science.

Nature·2026
関連記事をすべて見る

関連する実験動画

Updated: Jun 24, 2026

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons
10:29

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons

Published on: October 8, 2014

透明な濃厚ナトリウム

Yanming Ma1, Mikhail Eremets, Artem R Oganov

  • 1National Laboratory of Superhard Materials, Jilin University, Changchun 130012, China. mym@jlu.edu.cn

Nature
|March 13, 2009
PubMed
まとめ
この要約は機械生成です。

極度の圧力下では,ナトリウム (Na) が絶縁状態に変化し,以前の理論に異議を唱える. この予期せぬ介電相は,高密度で原子のペアリングではなく,電子の相互作用から生じる.

さらに関連する動画

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
08:17

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Published on: July 4, 2011

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
10:28

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Published on: June 30, 2016

関連する実験動画

Last Updated: Jun 24, 2026

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons
10:29

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons

Published on: October 8, 2014

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
08:17

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Published on: July 4, 2011

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
10:28

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Published on: June 30, 2016

科学分野:

  • 凝縮物質物理学 凝縮物質物理学
  • マテリアルサイエンス 材料科学
  • 高圧物理 高圧物理

背景:

  • 金属は,通常,原子間距離の増大と帯域の拡大により,圧力下での伝導性が向上します.
  • 高圧縮は,コア電子の重複につながり,電子特性を変化させ,潜在的に新しい相を誘導する可能性があります.
  • 以前の予測では,ナトリウム (Na) のようなアルカリ金属が,圧力下での原子のペアリングによって絶縁状態を形成することが示唆されていたが,これは未確認のままだった.

研究 の 目的:

  • 典型的な自由電子金属モデルを超えて,ナトリウム (Na) の高圧挙動を実験的に調査する.
  • 極度の圧縮下でのナトリウムの断熱状態への予測された変換を確認または反証する.
  • ナトリウムにおける観測された高圧相変異に起因する根本的なメカニズムを解明する.

主な方法:

  • ナトリウム (Na) を約200GPaまでの圧力にさらす.
  • 透明性の変化を検出するために,高圧下でのNaの光学特性を観察する.
  • 実験データと計算データを用いて,新相の電子構造と原子の配置を特徴づける.

主要な成果:

  • ナトリウム (Na) は,約200 GPa で光学的に透明な相に変容することが観察されました.
  • 新しいフェーズは,歪んだ二重六角の密集した構造を持つ広い帯域の隙間ダイエレクトリックとして識別されました.
  • 絶縁状態は,原子のペアリングではなく,バレンスの電子のp-dハイブリッド化とコア電子の反発に起因する.

結論:

  • 極端な圧縮は,ナトリウム (Na) のような単純な金属に,単純な帯域拡大や原子のペアリングを超えたメカニズムを通して,絶縁状態を誘導することができます.
  • 観測されたNaの介電相は,コア電子が高圧下において著しく重なり合うときに発生する複雑な電子の振る舞いを強調しています.
  • この発見は,圧力誘発の絶縁状態が,十分に強い圧縮下にある元素や化合物において一般的な現象である可能性があることを示唆している.