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Updated: Jun 24, 2026

Understanding the Development of Compensatory Pathways in a Mutant Malaria Parasite Harbouring Hypomorphic Allele of Plant-Like Kinases
09:13

Understanding the Development of Compensatory Pathways in a Mutant Malaria Parasite Harbouring Hypomorphic Allele of Plant-Like Kinases

Published on: November 22, 2024

プラズモディアム・ファルシパラムとヒトオロタート・フォスフォリボシルトランスフェラーゼの移行状態

Yong Zhang1, Minkui Luo, Vern L Schramm

  • 1Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Journal of the American Chemical Society
|March 19, 2009
PubMed
まとめ

プラズモディアム・ファルシパラムとヒトからのオロテート・フォスフォリボシルトランスフェラーゼ (OPRT) は,新しい抗マラリアおよび抗癌薬の開発のために研究されました. 計算分析により,それらの移行状態構造が明らかになり,新しい阻害剤の設計に役立ちました.

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