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Updated: Jan 8, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
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Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

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ALSの再考:TDP-43についてのFUS

Clotilde Lagier-Tourenne1, Don W Cleveland

  • 1Department of Cellular and Molecular Medicine, University of California San Diego, Ludwig Institute for Cancer Research, La Jolla, CA 92093-0670, USA.

Cell
|March 24, 2009
PubMed
まとめ

DNA/RNA結合タンパク質TDP-43およびFUS/TLSの変異は,遺伝性アミオトロフィック横筋硬化症 (ALS) と関連しています. これらの発見は,RNA処理の障害がALS発症の中心にあることを示唆しています.

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