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Updated: Jun 24, 2026

Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO
13:02

Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO

Published on: December 28, 2019

NEMOによる線形ユビキチン鎖の特定認識は,NF-kappaBの活性化にとって重要である

Simin Rahighi1, Fumiyo Ikeda, Masato Kawasaki

  • 1Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki, Japan.

Cell
|March 24, 2009
PubMed
まとめ

核因子-kappaB必須変調子 (NEMO) タンパク質は,そのUBANモチーフを通じて線形ユビキチン鎖を結合する. この相互作用は,NF-kappaBのシグナル伝達を活性化し,免疫に影響を与え,特定の遺伝疾患の説明に不可欠です.

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Detection of Protein Ubiquitination09:00

Detection of Protein Ubiquitination

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