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Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
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Zc3h12aは,mRNAの分解を調節することにより,免疫反応を制御するために不可欠なRNaseです

Kazufumi Matsushita1, Osamu Takeuchi, Daron M Standley

  • 1Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

Nature
|March 27, 2009
PubMed
まとめ

免疫応答変容体Zc3h12aは,免疫疾患を予防する必須のRNaseである. 炎症性遺伝子の安定性を制御し,マウスの欠乏は重度の貧血と自己免疫症状を引き起こす.

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