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Updated: Jun 10, 2026

Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices
10:04

Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices

Published on: October 29, 2012

ニコチン受容体チャネル開通を誘発する中間状態の検出とトラップ

Nuriya Mukhtasimova1, Won Yong Lee, Hai-Long Wang

  • 1Receptor Biology Laboratory, Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

Nature
|April 3, 2009
PubMed
まとめ

アセチルコリン受容体 (AChR) は,アゴニスト結合ではなく,2つのプライム状態を使用して,チャネルを開きます. このメカニズムは,迅速かつ効率的なシナプス伝達のためにアセチルコリン (ACh) による選択的活性化を可能にします.

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Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine10:48

Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine

Published on: January 25, 2019

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