経静脈冠動脈超音波画像撮影. 冠動脈の視覚化のための新しいアプローチ
K Sudhir1, P J Fitzgerald, J S MacGregor
1Cardiovascular Research Institute, University of California, San Francisco 94143-0124.
Circulation
|November 1, 1991
まとめ
静脈経静脈内超音波画像は,冠動脈を視覚化するための侵襲性の少ない方法を提供します. この有望な技術は,冠動脈血管の構造と形態の詳細な研究を可能にします.
科学分野:
- 心血管画像検査についてです.
- 医療用超音波検査について
- 介入性心臓病学 介入性心臓病学について
背景:
- カテーテルによる超音波検査は,血管内イメージングのために直接の動脈置換を必要とします.
- 冠動脈循環の詳細を調べるために,より侵襲的でないアプローチが必要である.
研究 の 目的:
- 血管内超音波を用いた心静脈系経由の冠動脈画像の可行性を評価する.
- 伝統的なカテーテル式超音波に対するより侵襲的でない代替手段を評価する.
主な方法:
- 5F (30MHz) のイメージングカテーテルを心臓静脈系 (冠動脈鼻腔,大心静脈,前腔間静脈) に置きました.
- 同時に光鏡を用いて,麻酔を受けた犬 (n=6) と人間の被験者 (n=11) に,右心臓のキャセテリゼーションを施した.
- 冠動脈 (周回動脈と左前部下降) は,隣接する心臓静脈から可視化されました.
主要な成果:
- 犬とヒトの両方の心臓静脈から冠動脈の視覚化に成功しました.
- 超音波で決定された横断面面積は,犬 (r=0.91) とヒト (r=0.82) の血管図と密接に相関していた.
- 超音波トランスデューサは,心臓の頂点までの前腔室間静脈に安全に前進させることができます.
結論:
- 経静脈内静脈超音波は,冠動脈の画像撮影のための実現可能で侵襲性の低いアプローチです.
- この技術は,冠動脈血管の構造と形態を研究するための有望な新しい方法を提供します.
- 潜在的な制限には,超音波の浸透問題と解剖学的変異が含まれます.
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