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Updated: Jun 24, 2026

Volumetric Imaging and Analysis of Primary Cilia in Musculoskeletal Tissue using the ARL13B-CENTRIN-2 Mouse Model
09:53

Volumetric Imaging and Analysis of Primary Cilia in Musculoskeletal Tissue using the ARL13B-CENTRIN-2 Mouse Model

Published on: March 28, 2025

脊椎動物のプライマリシリウム 発達,ホメオスタシス,病気の過程

Jantje M Gerdes1, Erica E Davis, Nicholas Katsanis

  • 1McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|April 7, 2009
PubMed
まとめ

脊椎動物のシリアは,細胞のシグナル伝達と発達に不可欠な,至るところに存在する器官である. 彼らの機能障害はヒトの遺伝疾患と関連しており,複雑な細胞の役割を強調しています.

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Using Primary Neurosphere Cultures to Study Primary Cilia

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Simple Detection of Primary Cilia by Immunofluorescence08:07

Simple Detection of Primary Cilia by Immunofluorescence

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Mechanism of Ciliary Motion01:05

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Mechanism of Ciliary Motion01:05

Mechanism of Ciliary Motion

The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
The cilia are made up of microtubules in a 9+2 arrangement, with nine microtubule doublet ring bundles, surrounding a pair of central singlet microtubule bundles. The doublet microtubule bundles are...
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