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Updated: Jun 24, 2026

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
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Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

分子内結合位移によるカルボサイクルの形成:範囲と機械的洞察

Lihong Wang1, Bodhuri Prabhudas, Derrick L J Clive

  • 1Chemistry Department, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.

Journal of the American Chemical Society
|April 8, 2009
PubMed
まとめ

この研究では,効率的な環形成のために,全炭素内分子結合位移反応 (ICD) を導入します. この新しい方法は,マイケルの加算とS(N) 2に似ている.

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Cycloaddition Reactions: Overview01:16

Cycloaddition Reactions: Overview

Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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Diels–Alder reactions between cyclic dienes locked in an s-cis configuration and dienophiles yield bridged bicyclic products.
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Cycloaddition Reactions: MO Requirements for Thermal Activation

Thermal cycloadditions are reactions where the source of activation energy needed to initiate the reaction is provided in the form of heat. A typical example of a thermally-allowed cycloaddition is the Diels–Alder reaction, which is a [4 + 2] cycloaddition. In contrast, a [2 + 2] cycloaddition is thermally forbidden.
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Intramolecular Aldol Reaction

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