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Updated: Jun 23, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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エナチオメリゼーションのダイナミクスと,N-トリメチラリル-2-リチオピロリジンの触媒的ダイナミック解像度

Timothy K Beng1, Taher I Yousaf, Iain Coldham

  • 1Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Arkansas 72701, USA.

Journal of the American Chemical Society
|May 2, 2009
PubMed
まとめ

研究者らは,キラルリガンドを用いてN-トリメチラリル-2-リチオピロリジンのエナティオメリゼーションバリアを測定した. 触媒的ダイナミック解像度が達成され,高エナティオメール比が93:7.7まで得られました.

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