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Updated: May 11, 2026

In Vitro Analysis of E3 Ubiquitin Ligase Function
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Rfu1: ユビキチン経済への刺激

Dieter A Wolf1, Matthew D Petroski

  • 1Burnham Institute for Medical Research, La Jolla, CA 92037, USA. dwolf@burnham.org

Cell
|May 5, 2009
PubMed
まとめ

細胞のストレスにより,モノウビキキチンに対する需要が増加します. 研究者らは,Rfu1タンパク質をダウンレギュレーションすることによってデウビキチン化酵素Doa4を阻害すると,酵母におけるストレス中にモノビキチンレベルが上昇することを発見した.

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