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Updated: Jun 23, 2026

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)
10:05

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)

Published on: January 20, 2016

アンドロゲン反応要素を標的としたサイクリックピロール-イミダゾールポリアミド

David M Chenoweth1, Daniel A Harki, John W Phillips

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

Journal of the American Chemical Society
|May 6, 2009
PubMed
まとめ

サイクルピロルイミダゾール (Py-Im) ポリアミドは,遺伝子調節に対する新しいアプローチを提供します. これらの細胞浸透性分子は,高親近性DNA結合を示し,遺伝子発現を効果的に調節し,治療応用において有望であることを示しています.

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Adrenergic Agonists: Chemistry and Structure-Activity Relationship

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