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Updated: Jun 23, 2026

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

[ミオグロビン,シトクロームb5] インターフェースの静電再設計により,タンパク質間電子の急速な移転を伴う,明確に定義されたドッキングされた複合体を作成します

Peng Xiong1, Judith M Nocek, Amanda K K Griffin

  • 1Northwestern University, Department of Chemistry, 2145 Sheridan Road, Evanston, Illinois 60208, USA.

Journal of the American Chemical Society
|May 8, 2009
PubMed
まとめ

研究者は,ミオグロビン (Mb) を改変して,シトクロームb5 (cyt b5) との相互作用を変化させた. 変異により,結合と電子伝送のメカニズムは,ダイナミックから単純なドッキングに移り,反応性が向上した.

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