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Updated: Jun 23, 2026

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
10:09

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

Published on: January 7, 2019

小分子阻害剤の複数の独立した結合部位がオンコタンパク質c-Myc上にある

Dalia I Hammoudeh1, Ariele Viacava Follis, Edward V Prochownik

  • 1Department of Chemistry, Georgetown University, Washington, District of Columbia 20057, USA.

Journal of the American Chemical Society
|May 13, 2009
PubMed
まとめ

研究者らは,小分子阻害剤のc-Mycオンコタンパク質に3つの異なる結合部位を特定しました. これらの部位は,同時に独立して結合し,c-Mycを保存することを可能にします.

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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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