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Updated: Jun 23, 2026

Quantification of Monocyte Transmigration and Foam Cell Formation from Individuals with Chronic Inflammatory Conditions
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Published on: October 17, 2017

CD11c+単細胞の機能的役割は,高コレステロール血症に関連したアテロゲネシスに起因する

Huaizhu Wu1, R Michael Gower, Hong Wang

  • 1Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

Circulation
|May 13, 2009
PubMed
まとめ

高コレステロールは,単細胞のCD11cを増加させ,単細胞の移動に不可欠なタンパク質である. CD11cをブロックすると,マウスモデルでの単細胞の蓄積と動脈硬化が減少し,心臓血管疾患におけるその役割が強調されます.

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