関連する実験動画

Updated: Jun 23, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
08:23

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds

Published on: February 16, 2022

2光子刺激による阻害されたニトロベンゼン誘導体からの光誘発性窒素酸化物放出

Kazuhiro Hishikawa1, Hidehiko Nakagawa, Toshiaki Furuta

  • 1Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori Mizuho-ku, Nagoya, Aichi 467-8603, Japan.

Journal of the American Chemical Society
|May 15, 2009
PubMed
まとめ

この研究は,特殊な化合物と2フォトン刺激 (TPE) レーザー光を使用して,酸化窒素 (NO) を生成する新しい方法を示しています. この方法は,潜在的なアプリケーションのために,NOの放出を正確に制御することができます.

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Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells

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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones07:30

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Electrophilic Aromatic Substitution: Nitration of Benzene

The nitration of benzene is an example of an electrophilic aromatic substitution reaction. It involves the formation of a very powerful electrophile, the nitronium ion, which is linear in shape. The reaction occurs through the interaction of two strong acids, sulfuric and nitric acid.
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All meta-directing substituents are deactivating groups. These substituents withdraw electrons from the aromatic ring, making the ring less reactive toward electrophilic substitution. For example, the nitration of nitrobenzene is 100,000 times slower than that of benzene because of the deactivating effect of the nitro group. The first step in an electrophilic aromatic substitution is the addition of an electrophile to form a resonance-stabilized carbocation. The energy diagrams for the...
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Nuclear Overhauser Enhancement (NOE)

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Photochemical Electrocyclic Reactions: Stereochemistry

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ortho–para-Directing Activators: –CH3, –OH, –⁠NH2, –OCH3

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Rate-Determining Steps

Relating Reaction Mechanisms
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The concept of rate-determining step can be understood from the analogy of a 4-lane freeway with a short-stretch of traffic-bottleneck caused due to...