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Updated: Jun 23, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
07:50

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

Published on: May 26, 2019

二次アルキル亜鉛ハライドとアリルブロミドおよび塩化物のネギシ結合

Chong Han1, Stephen L Buchwald

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|May 16, 2009
PubMed
まとめ

パラジウム触媒による新しい方法により,二次アルキル亜鉛ハライドとアリルハライドの効率的なネギシ結合が可能になる. このプロセスは,新しいCPhosリガンドを使用し,信頼性の高いC ((sp ((3)) -C ((sp ((2))) 結合形成のために望ましくない副作用を最小限に抑えます.

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