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Updated: May 5, 2026

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
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アバート&スイッチ:幹細胞の微分化におけるmiR-145

Raghu R Chivukula1, Joshua T Mendell

  • 1The McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|May 20, 2009
PubMed
まとめ

マイクロRNAは胚性幹細胞の再生を調節する. miR-145は,OCT4,SOX2およびKLF4の鍵となる多能性因子を阻害することによって,分化を促進し,自己更新を停止します.

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