三弁:現在の見通しと三弁の吐の管理の進化
Jason H Rogers1, Steven F Bolling
1Division of Cardiovascular Medicine, University of Davis Medical Center, 4860 Y St, Suite 2820, Sacramento, CA 95817, USA. jason.rogers@ucdmc.ucdavis.edu
Circulation
|May 28, 2009
まとめ
トリコスピッド吐症 (TR) はしばしば見過ごされますが,特にミトラ弁手術後の結果に大きく影響します. この見捨てられた弁性心疾患に対処するために,新しいトランスキャセター療法が必要である.
科学分野:
- 心臓病学 心臓病学
- 心臓外科手術について
- 介入性心臓病学 介入性心臓病学
背景:
- バルブ性心疾患の診断と治療は,特に大動脈,肺,ミトラル弁の経皮療法によって進歩しています.
- トリコスピッド吐 (TR) は,左側心不全と右心室過負荷に関連したトリコスピッド環の膨張によって頻繁に引き起こされます.
- ミトラバルブ手術中の未治療のTRは,手術前後の結果,機能クラス,生存を悪化させ,しばしば手術後も持続します.
研究 の 目的:
- トリコスピッドリグルジテーション (TR) の解剖学,病理生理学,および機械的矯正をレビューする.
- トランスキャセター療法によるTR治療の可能性を調査する.
- その臨床的意義にもかかわらず,TRの現在の無視を強調する.
主な方法:
- 三弁の解剖学とTR病理生理学に関する既存の文献のレビュー.
- 未治療または外科治療を受けたTRと関連したアウトカムの分析.
- 皮膚経由的なアプローチを含む現在のおよび潜在的な将来の治療方法の探索.
主要な成果:
- TRはしばしば環状膨張の結果であり,ミトラ弁手術だけでは確実に解決できません.
- ミトラバルブ手術中のTRの外科的矯正は効果的ですが,再手術は高い死亡率を伴う.
- ミトラル反吐のための新興のトランスキャセター療法では,TRに対する並列の皮膚経によるアプローチが必要になる可能性があります.
結論:
- トリコスピッドの嘔吐 (TR) は,しばしば治療が不十分である重要な臨床問題です.
- 潜在的にトランスキャセター介入によるTRの効果的な管理は,患者のアウトカムを改善するために不可欠です.
- 皮膚経由のTR療法のさらなる研究と開発は正当化されています.
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