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Updated: Jun 22, 2026

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ポリコンブ抑制におけるglycosyltransferase sxc/Ogtの重要な役割について

Maria Cristina Gambetta1, Katarzyna Oktaba, Jürg Müller

  • 1Gene Expression Programme, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Science (New York, N.Y.)
|May 30, 2009
PubMed
まとめ

ドロソフィラ遺伝子のスーパーセックスカンブス (sxc) は,O-リンクされたN-アセチルグルコサミン (O-GlcNAc) 移転酶 (Ogt) をコードする. O-GlcNAcの改変は,ポリコンブ群のタンパク質が発達中に転写抑制を維持するために不可欠です.

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