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Updated: Jun 22, 2026

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy
08:47

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy

Published on: December 7, 2017

ヒトのグルコース代謝におけるCHC22クラスリン重鎖イソフォームの役割

Stéphane Vassilopoulos1, Christopher Esk, Sachiko Hoshino

  • 1Department of Bioengineering and Therapeutic Sciences, University of California, School of Pharmacy, San Francisco (UCSF), San Francisco, CA 94143, USA.

Science (New York, N.Y.)
|May 30, 2009
PubMed
まとめ

クラトリンの重鎖同型CHC22は,ヒトの筋肉と脂肪のインスリン反応性GLUT4輸送に不可欠です. その機能障害は2型糖尿病と関連しており,種特有の経路を強調しています.

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Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice11:10

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Glucose Transporters01:27

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Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Glucose Homeostasis: Regulation of Blood Glucose01:02

Glucose Homeostasis: Regulation of Blood Glucose

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During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
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Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

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Membrane Proteins

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Glucose Absorption Into the Small Intestine

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Overview of Carbohydrate Metabolism

Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
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