関連する実験動画

Updated: Jun 22, 2026

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
09:14

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes

Published on: June 13, 2014

バクテリアはインテグリン結合キナーゼをハイジャックし,焦点結合を安定させ,細胞の脱離を阻害する

Minsoo Kim1, Michinaga Ogawa, Yukihiro Fujita

  • 1Department of Infectious Disease Control, International Research Center for Infectious Diseases, University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

Nature
|June 3, 2009
PubMed
まとめ

シゲッラ菌は OspE タンパク質を使用して宿主細胞の粘着性を高め,感染中に上皮細胞の脱離を防止します. インテグリン結合キナーゼ (ILK) とのこの相互作用は,細菌が感染性の足場を維持するのを助けます.

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