関連する実験動画

Updated: Jun 22, 2026

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
11:20

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry

Published on: March 29, 2018

ヒトの骨に結合するビスホスフォナートの熱力学: 2つのサイトモデル

Sujoy Mukherjee1, Cancan Huang, Francisco Guerra

  • 1Center for Biophysics & Computational Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

Journal of the American Chemical Society
|June 4, 2009
PubMed
まとめ

研究者は,イソテルミック・タイトレーション・カロリメトリー (ITC) を使用して,ビスフォスフォナートのヒトの骨への結合を研究した. 彼らは,2つの結合部位を特定し,結合はエントロピーによって引き起こされ,制御された骨の親和性を持つ新薬の設計を可能にしました.

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Covalent Binding of BMP-2 on Surfaces Using a Self-assembled Monolayer Approach

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Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain

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