メモリーCD8T細胞の消耗
Raymond M Welsh1, Liisa K Selin
1Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. raymond.welsh@umassmed.edu
Nature
|June 5, 2009
まとめ
繰り返された免疫接種は,既存の記憶細胞を傷つけることなく,メモリCD8T細胞を増加させることができます. しかし,複数の感染症により,メモリT細胞の総数は減少し,将来のワクチン接種戦略に影響を及ぼす可能性があります.
科学分野:
- 免疫学 免疫学とは
- ワクチン学 ワクチン学
背景:
- 免疫学的記憶の維持は,病原菌に対する生涯の保護に不可欠です.
- CD8T細胞は,適応免疫と免疫学的記憶において重要な役割を果たします.
- 既存の研究は,繰り返し接種した免疫が,記憶T細胞集団に与える影響について,矛盾する結果を示している.
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