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Updated: Jun 22, 2026

In Vitro Differentiation of Naive CD4+ T Cells into Pathogenic Th17 Cells in Mouse
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In Vitro Differentiation of Naive CD4+ T Cells into Pathogenic Th17 Cells in Mouse

Published on: October 25, 2024

ハロフギノンは,アミノ酸飢餓反応を活性化することによって,TH17細胞の分化を抑制する

Mark S Sundrud1, Sergei B Koralov, Markus Feuerer

  • 1Department of Pathology, Harvard Medical School and Immune Disease Institute, Boston, MA 02115, USA.

Science (New York, N.Y.)
|June 6, 2009
PubMed
まとめ

ハロフギノンは,アミノ酸飢餓反応 (AAR) を活性化することによって,炎症性Tヘルパー17 (TH17) 細胞の分化を選択的に抑制する. この標的型アプローチは,広範な免疫抑制なしで自己免疫病理を予防し,有望な治療戦略を提供します.

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