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Updated: Jun 22, 2026

Scaled-Up Preparation of an Intermediate of Upatinib, ACT051-3
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Published on: April 7, 2023

シタグリプチンの高効率の非対称合成

Karl B Hansen1, Yi Hsiao, Feng Xu

  • 1Department of Process Research, Merck Research Laboratory, Rahway, New Jersey 07065, USA.

Journal of the American Chemical Society
|June 11, 2009
PubMed
まとめ

2型糖尿病薬であるシタグリプチンの新しい緑色の合成が開発されました. この効率的なプロセスは,廃棄物とコストを削減しながら,高純度のシタグリプチンリン酸塩を生成します.

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