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Updated: Jun 22, 2026

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring
08:45

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring

Published on: November 17, 2018

LXRは,Idolに依存したLDL受容体のユビキチネーションを通じて,コレステロールの吸収を調節する

Noam Zelcer1, Cynthia Hong, Rima Boyadjian

  • 1Howard Hughes Medical Institute and Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.

Science (New York, N.Y.)
|June 13, 2009
PubMed
まとめ

肝臓のX受容体 (LXR) は,Idol経由でLDLの吸収を抑制することでコレステロールを調節し,LDL受容体を劣化させます. この発見は,コレステロールのホメオスタシスの新しい経路を明らかにしています.

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