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Updated: May 3, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
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プリオントポロジーと毒性について

Adriano Aguzzi1, Andrew D Steele

  • 1Institute of Neuropathology, University Hospital Zurich, Zurich, Switzerland. adriano.aguzzi@usz.ch

Cell
|June 16, 2009
PubMed
まとめ

E3ユビキチンリガゼであるマホグニンは,誤ったプリオンタンパク質によって不活性化されます. この無活性化は,致命的なスポンジ状脳症であるプリオン病の重要な特徴を説明します.

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