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Updated: Jun 22, 2026

A Visual Approach for Inducing Dolichoectasia in Mice to Model Large Vessel-Mediated Cerebrovascular Dysfunction
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アルツハイマー病における生理学と病理学の橋渡しである.

Dohoon Kim1, Li-Huei Tsai

  • 1Howard Hughes Medical Institute, MIT Picower Institute for Learning and Memory, Cambridge, MA 02139, USA.

Cell
|June 16, 2009
PubMed
まとめ

アルツハイマー病は,アミロイド前駆体タンパク質 (APP) の処理を伴う. 新しい発見は,APP製品であるN-APPとAbeta42が,神経系の発達とシナプス機能に影響を与えるリガンドとして作用することを明らかにしています.

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