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Updated: Mar 30, 2026

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System
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Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System

Published on: April 11, 2025

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RIP1-RIP3複合体のリン酸化駆動組成は,プログラムされた死滅とウイルス誘発の炎症を調節する

Young Sik Cho1, Sreerupa Challa, David Moquin

  • 1Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

Cell
|June 16, 2009
PubMed
まとめ

キナーゼRIP3は,細胞死経路であるプログラム性死滅に不可欠です. RIP3はRIP1のリン酸化を活性化し,ウイルスの感染中に炎症反応に不可欠なカスケードを開始します.

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Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis

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