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Updated: Jan 27, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
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セロトニントランスポーター遺伝子 (5-HTTLPR),ストレスの多い人生の出来事,うつ病のリスクとの相互作用:メタ解析

Neil Risch1, Richard Herrell, Thomas Lehner

  • 1Institute for Human Genetics, University of California at San Francisco, and Kaiser Permanente Northern California Division of Research, Oakland, USA.

JAMA
|June 18, 2009
PubMed
まとめ

このメタ解析では,セロトニントランスポーター遺伝子 (5-HTTLPR) のゲノタイプが,ストレスの多い人生の出来事と相互作用して,うつ病のリスクを増やすという証拠は見つかりませんでした. ストレスの多い人生の出来事だけがうつ病と関連していたが,遺伝子やストレスとの相互作用はそうではなかった.

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