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Updated: Jun 22, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
10:10

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

多能性因子Oct4はCtcfと相互作用し,X染色体のペアリングとカウントを制御します

Mary E Donohoe1, Susana S Silva, Stefan F Pinter

  • 1Howard Hughes Medical Institute, USA.

Nature
|June 19, 2009
PubMed
まとめ

主要な多能性因子であるOct4は,同類染色体のペアリングとカウントを調節することによって,X染色体不活性化 (XCI) を開始します. この発見は,Oct4を明らかにしています.

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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers10:28

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