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Updated: Jun 22, 2026

Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry
08:19

Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry

Published on: May 5, 2022

ミトコンドリアの機能障害は,鉄硫黄のクラスター欠陥によって核ゲノムの不安定化につながる

Joshua R Veatch1, Michael A McMurray, Zara W Nelson

  • 1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA.

Cell
|July 1, 2009
PubMed
まとめ

ミトコンドリア機能障害は,呼吸の欠如ではなく,酵母における核ゲノムの不安定性を引き起こします. この不安定性は,DNAの完全性にとって極めて重要な鉄硫黄のクラスター生物生成の障害と関連しています.

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Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

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