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9つのサブユニット複合体の形成は,HLAクラスIIのグリコプロテインと不変連鎖によって行われます

P A Roche1, M S Marks, P Cresswell

  • 1Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710.

Nature
|December 5, 1991
PubMed
まとめ

インヴァリアント鎖は,HLAクラスII分子と9つのサブユニット複合体を形成し,ペプチド結合と輸送に影響を与えます. この構造的組織は,免疫細胞のコミュニケーションの鍵です.

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Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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Antibodies consist of four polypeptide chains: two identical heavy...
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Protein Complexes with Interchangeable Parts

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Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

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The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order to...
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Antigens Involved in Adaptive Immunity

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Complete Antigens
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Antigen Processing Pathways

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