関連する実験動画

Updated: Jun 14, 2026

Cholesterol Efflux Assay
07:54

Cholesterol Efflux Assay

Published on: March 6, 2012

レシチン:コレステロールアシルトランスフェラーゼ発現は,マクロファージの逆コレステロール輸送に微小な影響を及ぼす in vivo

Hiroyuki Tanigawa1, Jeffrey T Billheimer, Jun-ichiro Tohyama

  • 1Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

Circulation
|July 1, 2009
PubMed
まとめ

レシチン:コレステロールアシルトランスフェラーゼ (LCAT) の過剰発現は,マクロファージの逆コレステロール輸送 (RCT) を強化しません. LCAT欠乏症でも,RCTは50%しか減少しないので,LCATは以前考えられていたよりもマクロファージRCTにとってより重要ではないことを示唆しています.

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