Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Chain Reactions01:29

Chain Reactions

Chain reactions involve highly reactive transient species, such as atoms or free radicals, as intermediates. These intermediates facilitate rapid reactions over an extended period. The process includes a series of steps: a reactive intermediate is consumed, reactants are converted to products, and the intermediate is regenerated. This cycle enables continuous repetition, amplifying the production of products with a small amount of intermediate. Chain reactions often utilize free radicals as...
Radical Chain-Growth Polymerization: Overview01:10

Radical Chain-Growth Polymerization: Overview

Chain-growth or addition polymerization is successive addition reactions of monomers with a polymer chain. In radical chain-growth polymerization, the reaction proceeds via a free-radical intermediate. The free radical is formed from radical initiators, which spontaneously generate free radicals by homolytic fission. Organic peroxides (such as dibenzoyl peroxide, as shown in Figure 1) or azo compounds are popular radical initiators. A low concentration ratio of radical initiator to monomer is...
Radical Chain-Growth Polymerization: Chain Branching01:17

Radical Chain-Growth Polymerization: Chain Branching

The skeletal structure of polymers synthesized via radical polymerization is always branched. For example, the polymerization of ethylene by radical polymerization results in a low-density grade of polyethylene with a heavily branched skeletal structure. Here, the radical site abstracts hydrogen from the growing chain, and the radical site shifts from the end (a primary carbon center) to anywhere within the growing chain (a secondary carbon center). Consequently, the part of the chain from the...
Radical Chain-Growth Polymerization: Mechanism01:09

Radical Chain-Growth Polymerization: Mechanism

The radical chain-growth polymerization mechanism consists of three steps: initiation, propagation, and termination of polymerization. The polymerization initiates when a free radical generated from the radical initiator adds to the unsaturated bond in the monomer. The unpaired electron of the free radical and one π electron in the unsaturated bond creates a σ bond between the free radical and the monomer. As a result, the other π electron in the unsaturated bond converts this species into the...
Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the generated carbocation,...
Anionic Chain-Growth Polymerization: Mechanism01:04

Anionic Chain-Growth Polymerization: Mechanism

The mechanism for anionic chain-growth polymerization involves initiation, propagation, and termination steps. In the initiation step, a nucleophilic anion, such as butyl lithium, initiates the polymerization process by attacking the π bond of the vinylic monomer. As a result, a carbanion, stabilized by the electron‐withdrawing group, is generated. The resulting carbanion acts as a Michael donor in the propagation step and attacks the second vinylic monomer, which acts as a Michael acceptor.

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Electronegatively substituted adamantyl units accelerate chemiexcitation of 1,2-dioxetane luminophores while preserving chemical stability.

Chemical science·2026
Same author

Chemiluminescent Probes Allow for the Rapid Identification of Colibactin-Producing Bacteria.

JACS Au·2026
Same author

Sunlight-powered photodynamic therapy for painless diabetic wound care.

National science review·2026
Same author

A chemiluminescence assay targeting granzyme A activity for monitoring inflammatory bowel disease.

Nature biomedical engineering·2026
Same author

Chemiluminescent probes allow for the rapid identification of colibactin-producing bacteria.

bioRxiv : the preprint server for biology·2026
Same author

Chemiluminescent probes for imaging cysteine cathepsin activity.

Bioorganic & medicinal chemistry letters·2025
Same journal

Switching Site Selectivity in Alkoxyamine Hydration: From Lone-Pair Direction to Solvent Network Dominance.

Journal of the American Chemical Society·2026
Same journal

A Topotactic Leap: 2D Layers to 3D Large-Pore Zeolite.

Journal of the American Chemical Society·2026
Same journal

Enhanced Hydrogen Evolution over Single-Atom Catalysts via Electrostatic Polarization in Contact-electro-catalysis.

Journal of the American Chemical Society·2026
Same journal

Tumor Acidity-Activatable Ionizable Lipid Nanoparticles for Selective Oncolytic Therapy.

Journal of the American Chemical Society·2026
Same journal

Alternating Magnetic Field Promotes Ammonia Cracking by Disrupting the Sabatier Limitation of Ruthenium Catalytic Species.

Journal of the American Chemical Society·2026
Same journal

Bulk Ferromagnetic Icosahedral Quasicrystals without Rapid Quenching.

Journal of the American Chemical Society·2026
関連記事をすべて見る

関連する実験動画

Updated: Jun 22, 2026

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

デンドリット連鎖反応 (Dendritic Chain Reaction) とは

Eran Sella1, Doron Shabat

  • 1School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel-Aviv University, Tel Aviv 69978, Israel.

Journal of the American Chemical Society
|July 3, 2009
PubMed
まとめ
この要約は機械生成です。

この研究は,水性環境における指数関数信号増幅のための,PCRベースの dendritic chain reaction (DCR) ではない新しい,新しい方法を紹介しています. この方法は,単一の分析分子から強力な信号を生成することによって,診断感度を高めます.

さらに関連する動画

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

The Analysis of Purkinje Cell Dendritic Morphology in Organotypic Slice Cultures
07:59

The Analysis of Purkinje Cell Dendritic Morphology in Organotypic Slice Cultures

Published on: March 21, 2012

関連する実験動画

Last Updated: Jun 22, 2026

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

The Analysis of Purkinje Cell Dendritic Morphology in Organotypic Slice Cultures
07:59

The Analysis of Purkinje Cell Dendritic Morphology in Organotypic Slice Cultures

Published on: March 21, 2012

科学分野:

  • バイオケミストリー バイオケミストリー
  • アナリティカル・ケミストリー (Analytical Chemistry) とは
  • 分子診断は分子診断です.

背景:

  • 信号増幅は,診断における分析剤検出感度を改善するために不可欠です.
  • 既存の方法は,しばしばポリメラーゼ連鎖反応 (PCR) に基づくか,水以外の条件を必要とする.
  • 水性環境では,PCRフリーで敏感な増幅技術が必要である.

研究 の 目的:

  • 指数関数信号増幅のための新しいPCRベースのモジュール技術を開発する.
  • 水中の環境で信号の増幅を実証するために.
  • 診断目的で技術の感度を評価する.

主な方法:

  • 自己燃焼性デンドリマーの分解に基づくデンドリト連鎖反応 (DCR) の開発.
  • 探知可能な信号を生成するために,デンドリマー分解時にクロモゲン分子の放出.
  • DCRテクニックとプロテアゼ診断用プローブを組み合わせる.

主要な成果:

  • DCR技術は,水中の条件下で診断信号の指数関数的な増幅を可能にします.
  • 分析物質の単一の分子は,DCRを起動し,強力な信号を生成します.
  • DCR法を使用してペニシリン-G-アミダースの活性を検出する際に高い感度を達成しました.

結論:

  • 開発されたDCRテクニックは,PCRフリーで敏感な信号増幅のための新しいアプローチを提供します.
  • この方法は,水性環境での診断用途に適しています.
  • この技術は,非PCRベースの診断信号増幅における重要な進歩を表しています.