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Updated: Apr 30, 2026

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エストロゲン受容体βの活性化により,心臓保護に関与するタンパク質のS-ニトロシル化が生じる

Jeffrey Lin1, Charles Steenbergen, Elizabeth Murphy

  • 1Harvard Medical School, Boston, MA, USA.

Circulation
|July 8, 2009
PubMed
まとめ

エストロゲン受容体β (ER-β) の活性化は,タンパク質S-ニトロシル化 (SNO) を増加させることで,心臓をイシュケミア/リパーフュージョン損傷から保護する. このメカニズムは,長期的なエストロゲン媒介の心臓保護におけるER-βと酸化窒素のシグナリングを強調しています.

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