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Ni,Feを含む一酸化炭素脱水原酶のシアン化物阻害の構造的基礎

Jae-Hun Jeoung1, Holger Dobbek

  • 1Labor für Bioanorganische Chemie, Universität Bayreuth, 95447 Bayreuth, Germany.

Journal of the American Chemical Society
|July 9, 2009
PubMed
まとめ

シアニドは,C-クラスターのニッケルイオンと結合することによって,一酸化炭素脱水酸化酵素 (CODHs) を阻害する. この結合は基板へのアクセスを阻害し,構造の変化を引き起こし,その抑制効果を説明します.

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