関連する実験動画

Updated: Jun 20, 2026

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines
06:00

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines

Published on: September 13, 2017

骨髄性腫瘍における変異したC-CBL腫瘍抑制剤の機能増強

Masashi Sanada1, Takahiro Suzuki, Lee-Yung Shih

  • 1Cancer Genomics Project, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

Nature
|July 22, 2009
PubMed
まとめ

骨髄性腫瘍における得られた単親分裂症 (aUPD) は,C-CBL腫瘍抑制体の新しい機能獲得変異と関連しています. これらの変異は,血液生成幹細胞のサイトカイン感受性を高め,がんの発症を誘発する.

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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs10:44

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

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