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Updated: Jun 21, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
11:37

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

Published on: November 29, 2013

高度保存されたヒスティジンは,タンパク質のスプライシングにおける二重の触媒的役割を果たす:pKaシフトメカニズムである

Zhenming Du1, Philip T Shemella, Yangzhong Liu

  • 1Biology Department, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.

Journal of the American Chemical Society
|July 28, 2009
PubMed
まとめ

タンパク質のスプライシングはヒスティジン残基に依存しています. この研究では,ヒスティジンの重要な成分が明らかになりました.

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Conserved Binding Sites

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Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally analyses the...
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Chromatin Structure Regulates pre-mRNA Processing

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The chromatin structure, especially...
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Allosteric Proteins-ATCase

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Conservation of Protein Domains Over Different Proteins

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