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Updated: May 7, 2026

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
11:25

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice

Published on: April 1, 2015

MafBは,血液生成幹細胞のM-CSFに依存する筋膜結束分裂を制限する

Sandrine Sarrazin1, Noushine Mossadegh-Keller, Taro Fukao

  • 1Centre d'Immunologie de Marseille-Luminy, Université Aix-Marseille, Campus de Luminy, Case 906, 13288 Marseille Cedex 09, France.

Cell
|July 28, 2009
PubMed
まとめ

転写因子MafBは,血液形成性幹細胞 (HSC) の分裂を制御し,特に骨髄系統へのコミットメントを制限する. MafB欠乏症は,M-CSFに対するHSCの感受性を高め,骨髄単細胞の再生を促進します.

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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

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Database-guided Flow-cytometry for Evaluation of Bone Marrow Myeloid Cell Maturation

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