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Neisseria gonorrhoeaeのピリン抗原変異には,代替のDNA構造が必要である

Laty A Cahoon1, H Steven Seifert

  • 1Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA.

Science (New York, N.Y.)
|August 8, 2009
PubMed
まとめ

Neisseria gonorrhoeaeのような病原性細菌は,表面タンパク質の抗原変異 (Av) のためにDNA再結合を使用します. 研究者らは,この免疫回避メカニズムに不可欠なG4構造を形成するGに富んだDNA配列を発見した.

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