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Updated: May 11, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
09:32

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development

Published on: June 15, 2017

IRE1αキナーゼの活性化モードは,異なった細胞運命を決定するために,代替のエンドロビヌクレアゼ出力を制御します

Dan Han1, Alana G Lerner, Lieselotte Vande Walle

  • 1Department of Medicine, University of California, San Francisco, San Francisco, CA 94143-2520, USA.

Cell
|August 12, 2009
PubMed
まとめ

展開されたタンパク質応答 (UPR) は,エンドプラズマ網膜 (ER) ストレス中に細胞死を引き起こす可能性があります. キナーゼ阻害剤は,IRE1alpha RNaseの活動を変化させ,細胞生存を促進することによって,このアポプトーシスをブロックすることができます.

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