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Updated: Apr 2, 2026

Efficient iPS Cell Generation from Blood Using Episomes and HDAC Inhibitors
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p53-p21経路による誘発性多能幹細胞生成の抑制

Hyenjong Hong1, Kazutoshi Takahashi, Tomoko Ichisaka

  • 1Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto 606-8507, Japan.

Nature
|August 12, 2009
PubMed
まとめ

p53 (腫瘍抑制剤) を抑制すると,様々な細胞タイプから誘発された多能幹細胞 (iPS) の生成が著しく強化されます. この発見は,p53を明らかにしています.

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