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Updated: Jun 21, 2026

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry
05:45

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry

Published on: June 8, 2021

水素/デウテリウム交換質量スペクトロメトリーは,17 kDa のタンパク質の構造的移行を特徴付けるために,上から下への電子捕獲解離を用いて行われます

Jingxi Pan1, Jun Han, Christoph H Borchers

  • 1Department of Chemistry, The University of Western Ontario, London, ON, N6A 5B7, Canada.

Journal of the American Chemical Society
|August 13, 2009
PubMed
まとめ

この研究は,タンパク質構造分析のための上下電子捕獲解離 (ECD) 質量スペクトロメトリ (MS) を導入します. この高度な方法は,従来の技術と比較して,アミドH/D交換 (HDX) 研究により高い解像度を提供します.

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