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Updated: Jun 20, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

カリケアミシンポリケチド合成酵素CalE8によるオクタケチドポリエンの生成:エネディイン核構造の生物合成への影響

Katherine Belecki1, Jason M Crawford, Craig A Townsend

  • 1Department of Chemistry, The Johns Hopkins University, Baltimore, Maryland 21218, USA.

Journal of the American Chemical Society
|August 20, 2009
PubMed
まとめ

エネダイネ抗生物質のバイオシンセシスは,これまで考えられていた以上に収束している可能性があります. 10基のカリケアミシンの生成に関与する酵素は,通常9基のエネディイン系で見られる化合物も作ることができます.

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