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Updated: Aug 10, 2026

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos
07:24

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

腫瘍特異的なリンパ腫の増殖抑制は,反感覚オリゴデオキシヌクレオチドによって行われます

M E McManaway1, L M Neckers, S L Loke

  • 1Pediatric Branch, National Cancer Institute, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892.

Lancet (London, England)
|April 7, 1990
PubMed
まとめ

バーキットリンパ腫における異常なc-mycRNAを標的としたアンチセンセスのオリゴヌクレオチドは,癌細胞の増殖を著しく抑制した. この標的型アプローチは,正常細胞に影響を与えることなく,腫瘍特異のc-mycタンパク質を減少させ,がん治療の可能性を示した.

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Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells09:37

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

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