Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Genetic and Environmental Influences on the Affective Regulation Network: A Prospective Experience Sampling Analysis.

Frontiers in psychiatry·2018
Same author

Neurobehavioural mechanisms of threat generalization moderate the link between childhood maltreatment and psychopathology in emerging adulthood

Journal of psychiatry & neuroscience : JPN·2018
Same author

Childhood adversities and psychotic symptoms: The potential mediating or moderating role of neurocognition and social cognition.

Schizophrenia research·2018
Same author

Patterns of obsessive-compulsive symptoms and social functioning in schizophrenia; a replication study.

Psychiatry research·2018
Same author

Alpha7 acetylcholine receptor autoantibodies are rare in sera of patients diagnosed with schizophrenia or bipolar disorder.

PloS one·2018
Same author

Assessing cross-national invariance of the Community Assessment of Psychic Experiences (CAPE).

Psychological medicine·2018
Same journal

Rethinking anticoagulation intensity during extracorporeal membrane oxygenation.

Lancet (London, England)·2026
Same journal

Standard-dose unfractionated heparin versus low-dose unfractionated heparin and low-molecular-weight heparin in extracorporeal life support (RATE): an open-label, randomised, non-inferiority trial.

Lancet (London, England)·2026
Same journal

Inherited retinal degenerations: clinical phenotypes and emerging therapies.

Lancet (London, England)·2026
Same journal

Documenting hospice care.

Lancet (London, England)·2026
Same journal

After the wood chipper.

Lancet (London, England)·2026
Same journal

Assisted dying and the silencing of medicine's next generation.

Lancet (London, England)·2026
関連記事をすべて見る

関連する実験動画

Updated: Jun 20, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

統合失調症 統合失調症 統合失調症

Jim van Os1, Shitij Kapur

  • 1Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, Netherlands. j.vanos@sp.unimaas.nl

Lancet (London, England)
|August 25, 2009
PubMed
まとめ
この要約は機械生成です。

統合失調症の研究は,生物学的,疫学的,および薬理学的側面についての理解を前進させています. 現在の治療法では幻覚のような症状を治すことができるが,病気を治すことはできず,総合的なケアが必要となる.

さらに関連する動画

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

関連する実験動画

Last Updated: Jun 20, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

科学分野:

  • 神経科学は神経科学である.
  • 精神科医は精神病を患っている.
  • 遺伝学 遺伝学とは

背景:

  • 統合失調症は複雑な精神障害であり,人間と社会に重大なコストを伴う.
  • 症状は,青春期または成人期の初期にしばしば現れ,集団全体で発生率とプレゼンテーションが異なる.
  • 双極性障害や自閉症のような発達障害に遺伝的関連がある.

研究 の 目的:

  • 統合失調症の生物学,流行病学,および薬理学の重要な進展をレビューする.
  • これらの相互に関連した側面を理解するための症候群的枠組みを提供すること.
  • 現在の治療効果と将来の研究方向性を強調する.

主な方法:

  • 統合失調症に関する生物学的,疫学的,および薬理学的研究のレビュー.
  • 他の精神病および発達障害との遺伝的重複の分析.
  • 神経生物学的基礎,特にドーパミン系の変化の検討.

主要な成果:

  • 統合失調症の診断は,脳の構造の変化やドーパミンシステムの変化と相関しており,ポジティブな症状に関連しています.
  • ドーパミンを標的とする抗精神病薬は妄想や幻覚には効果があるが,認知/動機付けの欠陥には効果がない.
  • 職業的および心理的なサポートを含む統合的介入は,機能的な結果を改善します.

結論:

  • 研究は,統合失調症の症状の生物学的メカニズムと心理的モデレーターを解明し始めています.
  • 現在の治療法では,治癒ではなく症状のコントロールができますが,長期の入院はしばしば不要です.
  • 統合失調症の予後は,適切な管理で,これまで考えられていたよりも有利です.