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Updated: Jun 20, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

c-kit腫瘍遺伝子のプロモーター内のGに富んだ配列は,非対称なGテトラドダイナミクスを持つ平行G四重複体を形成する

Shang-Te Danny Hsu1, Peter Varnai, Anthony Bugaut

  • 1University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, United Kingdom.

Journal of the American Chemical Society
|August 27, 2009
PubMed
まとめ

グアニンに富んだDNA配列は,遺伝子プロモーターのG四重複構造を形成する. この研究は,c-kit2 G-四重複体が,類似した構造のダイナミックな集合体として存在することを明らかにし,腫瘍遺伝子の調節を理解するために重要である.

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